| Product Name | LONP1 Monoclonal Antibody |
|---|---|
| Description | LONP1(Lon protease homolog,mitochondrial) is also named as LONP,LONHS,HLON,LON,PRSS15,PIM1,MGC1498 and belongs to the peptidase S16 family. It seems to play a major role in the elimination of oxidatively modified proteins in the mitochondrial matrix. LONP1,also a nuclearly encoded and mitochondrially located stress-responsive protease,is involved in heme-mediated ALAS-1 turnover. It recognizes specific surface determinants or folds,initiates proteolysis at solvent-accessible sites,and generates unfolded polypeptides that are then processively degraded. |
| Synonyms | hLON,LON,lon peptidase 1,mitochondrial,Lon protease like protein,LonHS,LONP,LONP1,PIM1,PRSS15,Serine protease 15 |
| Host | Mouse |
| Clone | 3200 |
| Immunogen | Fusion protein of LONP1 |
| Isotype | IgG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P36776 |
| Background | LONP1(Lon protease homolog,mitochondrial) is also named as LONP,LONHS,HLON,LON,PRSS15,PIM1,MGC1498 and belongs to the peptidase S16 family. It seems to play a major role in the elimination of oxidatively modified proteins in the mitochondrial matrix. LONP1,also a nuclearly encoded and mitochondrially located stress-responsive protease,is involved in heme-mediated ALAS-1 turnover. It recognizes specific surface determinants or folds,initiates proteolysis at solvent-accessible sites,and generates unfolded polypeptides that are then processively degraded. |
| Supplier | Elabscience |
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