| Product Name | Lysozyme |
|---|---|
| Description | This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the anti-microbial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. Missense mutations in LYZ have been identified in heritable renal amyloidosis. Lysozyme occurs in specific granules of human polymorphonuclear leukocytes and takes part in the antibacterial activity of the leukocytes. It hydrolyzes beta-1,4 links between N-acetylmuramic acid or 2-acetamido-2deoxy-D-glucose residues in mucopolysacchride, mucopolypeptide or chitin |
| Synonyms | LYZ, LZM |
| Molecular Weight | 17000 |
| Biological Activity | Activity: 30,000 Sugar units per mg. One unit is defined as the amount of enzyme that digest powdered cells of Micrococcus lysodeikticus, causing a decrease in absorbancy of 0.001 per minute at 37oC , pH 7.0 |
| Form | Lyophilized purified protein, from 52.6 ?l 50mM Sodium Acetate, pH 6.0, with 100mM NaCl |
| Purity | 95% by SDS-PAGE |
| Storage | -2°C (aliquot) |
| Notes | Because no test method can offer complete assurance that products derived from human source will not transmit infectious agents, it is recommended that this product be handled with the same precautions used for patient specimens. |
| Background | This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the anti-microbial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. Missense mutations in LYZ have been identified in heritable renal amyloidosis. |
| Supplier | ARP |
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