| Product Name | LYVE1, 25-235aa, Human, Recombinant, Hi-5 cell |
|---|---|
| Description | Lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1), a selective marker of the lymphatic endothelium, is a surface endocytic receptor for hyaluronan (HA), which is an extracellular glycosaminoglycan involved in cell adhesion and migration. LYVE1 is also known as XLKD1 and may function in lympathic hyaluronan transport and have a role in tumor metastasis. Recombinant human LYVE1 was expressed in High Five insect cells and purified by conventional chromatography techniques. As a result of glycosylation, the size of molecular weight will be shift-up as an approximately 50 kDa on SDS-PAGE analysis. |
| Synonyms | CRSBP-1, HAR, LYVE-1, XLKD1, Lymphatic vessel endothelial hyaluronan receptor 1, LYVE1, Lymphatic vessel endothelial hyaluronan receptor 1 CRSBP 1, CRSBP1, extracellular link domain containing 1, extracellular link domain-containing 1, hyaluronic acid receptor, LYVE 1, Lymphatic endothelium specific hyaluronan receptor. |
| Host | E. coli |
| Molecular Weight | 15 kDa (132 aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | ADPLRAEELS IQVSCRIMGI TLVSKKANQQ LNFTEAKEAC RLLGLSLAGK DQVETALKAS FETCSYGWVG DGFVVISRIS PNPKCGKNGV GVLIRKVPVS RQFAAYCYNS SDTWTNSCIP EIITTKDPIF NTQTATQTTE FIVSDSTYSV ASPYSTIPAP TTTPPAPAST SIPRRKKLIC VTEVFMETST MSTETEPFVE NKAAFKNEAA GFGGSGRLVP RGSHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 25 mM Tris-HCl (pH7.5) 100mM NaCl |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Chen L. et al. (2005) Invest. Ophthalmol Vis. Sci. 46, 4536-4540. Banerji S. et al. (1999) J. Cell Biol. 144, 789-801. |
| Background | Lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1), a selective marker of the lymphatic endothelium, is a surface endocytic receptor for hyaluronan (HA), which is an extracellular glycosaminoglycan involved in cell adhesion and migration. LYVE1 is also known as XLKD1 and may function in lympathic hyaluronan transport and have a role in tumor metastasis. Recombinant human LYVE1 was expressed in High Five insect cells and purified by conventional chromatography techniques. As a result of glycosylation, the size of molecular weight will be shift-up as an approximately 50 kDa on SDS-PAGE analysis. |
| Supplier | ARP |
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