| Product Name | MAD2L2 Antibody, FITC conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against MAD2L2 conjugated to FITC |
| Synonyms | Homolog of REV7 S cerevisiae antibody; hREV7 antibody; MAD2 (mitotic arrest deficient yeast, homolog) like 2 antibody; MAD2 homolog antibody; MAD2 like 2 antibody; MAD2 mitotic arrest deficient like 2 antibody; MAD2-like protein 2 antibody; MAD2B antibody; Mad2l2 antibody; MD2L2_HUMAN antibody; Mitotic Arrest Deficient 2 L2 antibody; Mitotic arrest deficient 2-like protein 2 antibody; Mitotic arrest deficient homolog like 2 antibody; Mitotic arrest deficient like 2 (yeast) antibody; Mitotic arrest deficient yeast homolog antibody; Mitotic spindle assembly checkpoint protein MAD2B antibody; Polymerase (DNA directed) zeta 2 accessory subunit antibody; POLZ2 antibody; REV 7 antibody; REV7 antibody; REV7 homolog antibody; Weakly similar to Mitotic MAD2 protein (S cerevisiae) antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | FITC |
| Immunogen | Recombinant human Mitotic spindle assembly checkpoint protein MAD2B protein (1-211AA) |
| Isotype | IgG |
| Target | MAD2L2 |
| Reactivity | Human |
| Applications | ELISA, Dot Blot |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9UI95 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation. |
| Supplier | Cusabio |
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