| Product Name | MAS1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to MAS1 |
| Synonyms | MAS antibody; MAS proto oncogene antibody; Mas-related G protein-coupled receptor A antibody; MAS_HUMAN antibody; Mas1 antibody; MAS1 oncogene antibody; MAS1 proto-oncogene; G protein-coupled receptor antibody; MGRA antibody; Proto-oncogene Mas antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Proto-oncogene Mas protein (246-325AA) |
| Isotype | IgG |
| Target | MAS1 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | P04201 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. |
| Supplier | Cusabio |
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