MCM3AP Antibody

Category: Antibodies
Catalog
CSB-PA107336
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Product Name MCM3AP Antibody
Description Rabbit polyclonal antibody to MCM3AP
Synonyms 80 kDa MCM3 associated protein antibody; 80 kDa MCM3-associated protein antibody; FLJ44336 antibody; FLJ45306 antibody; Germinal center associated nuclear protein antibody; KIAA0572 antibody; MAP80 antibody; MCM3 import protein antibody; MCM3 minichromosome maintenance deficient 3 associated protein antibody; MCM3A antibody; MCM3A_HUMAN antibody; Mcm3ap antibody; Minichromosome maintenance complex component 3 associated protein antibody; Minichromosome maintenance deficient 3 associated protein antibody; Minichromosome maintenance protein 3 associated protein antibody; Protein GANP antibody; SAC3 antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Fusion protein of human MCM3AP
Isotype IgG
Target MCM3AP
Reactivity Human
Applications ELISA, IHC, WB
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot O60318
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
Supplier Cusabio

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