Product Name | MED24 Antibody |
---|---|
Description | Rabbit polyclonal antibody to MED24 |
Synonyms | CRSP complex subunit 4 antibody; Activator recruited cofactor 100 kDa component antibody; Activator-recruited cofactor 100 kDa component antibody; ARC100 antibody; Cofactor required for Sp1 transcriptional activation subunit 4 antibody; CRSP complex subunit 4 antibody; CRSP100 antibody; CRSP4 antibody; DRIP100 antibody; hTRAP100 antibody; KIAA0130 antibody; MED 24 antibody; MED24 antibody; MED24_HUMAN antibody; Mediator complex subunit 24 antibody; Mediator of RNA polymerase II transcription subunit 24 antibody; Mediator of RNA polymerase II transcription subunit 24 homolog antibody; MGC8748 antibody; OTTHUMP00000164458 antibody; OTTHUMP00000164460 antibody; THRAP4 antibody; Thyroid hormone receptor associated protein 4 antibody; Thyroid hormone receptor associated protein complex 100 kDa component antibody; Thyroid hormone receptor-associated protein 4 antibody; Thyroid hormone receptor-associated protein complex 100 kDa component antibody; Trap100 antibody; Trapp100 antibody; Vitamin D3 receptor interacting protein complex component DRIP100 antibody; Vitamin D3 receptor-interacting protein complex 100 kDa component antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthesized peptide derived from internal of human MED24. |
Isotype | IgG |
Target | MED24 |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, IF, WB |
Form | liquid |
Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Uniprot | O75448 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998). Rachez C., Genes Dev. 12:1787-1800(1998). Nagase T., DNA Res. 2:167-174(1995). |
Supplier | Cusabio |
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