| Product Name | Melanin concentrating hormone (human, mouse, rat) |
|---|---|
| Description |
Melanin concentrating hormone (human, mouse, rat) is the endogenous agonist at melanin concentration hormone receptors, with IC50 values of 0.3 and 1.5 nM and EC50 values of 3.9 and 0.1 nM at MCH-R1 and MCH-R2 receptors respectively. Melanin concentrating hormone receptors are expressed in the central and peripheral nervous systems and melanin concentrating hormone plays an important role in the control of feeding, energy metabolism, body weight regulation, anxiety, sleep, and reward. |
| Synonyms | MCH (human, mouse, rat) |
| Molecular Weight | 2386.84 Da |
| Target | Melanin concentrating hormone receptors |
| Amino Acid Sequence | DFDMLRCMLGRVYRPCWQV |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 128315-56-0 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: Disulfide bridge between cyteines 7 and 16 |
| References |
Chung S et al. (2011) Recent updates on the melanin-concentrating hormone (MCH) and its receptor system: lessons from MCH1R antagonists. J. Mol. Neurosci. 43 115 PMID:20582487Diniz and Bittencourt (2017) The Melanin-Concentrating Hormone as an Integrative Peptide Driving Motivated Behaviors. Front Syst Neurosci. 11 32 PMID: 28611599Diniz and Bittencourt (2019) The Melanin-Concentrating Hormone (MCH) System: A Tale of Two Peptides. Front Neurosci. 13 1280 PMID: 31849590 Related areas All peptides >All melanin concentrating hormone receptor modulators >All endocrinology research categories >All neuroscience research categories >All appetite regulation research categories > |
| Supplier | Isca Biochemicals Limited |
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