| Product Name | Meteorin, 22-291aa, Mouse, Baculovirus |
|---|---|
| Description | METRN, also known as meteorin, involved in both glial cell differentiation and axonal network formation during neurogenesis. It promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also, this protein induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Recombinant mouse METRN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Metrn, 1810034B16Rik, Hyrac |
| Host | Virus |
| Molecular Weight |
81.6kDa (730aa) 70-100KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | GYSEDRCSWR GSGLTQEPGS VGQLTLDCTE GAIEWLYPAG ALRLTLGGPD PGTRPSIVCL RPERPFAGAQ VFAERMTGNL ELLLAEGPDL AGGRCMRWGP RERRALFLQA TPHRDISRRV AAFRFELHED QRAEMSPQAQ GLGVDGACRP CSDAELLLAA CTSDFVIHGT IHGVAHDTEL QESVITVVVA RVIRQTLPLF KEGSSEGQGR ASIRTLLRCG VRPGPGSFLF MGWSRFGEAW LGCAPRFQEF SRVYSAALTT HLNPCEMALD HHHHHH |
| Tag | His-tag |
| Reactivity | Mouse |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Wang Z et al., (2012) J. Cereb. Blood Flow Metab. 32(2):387-398. Lee HS et al., (2010) J. Cell. Sci. 123(PT11):1959-1968. |
| Background | METRN, also known as meteorin, involved in both glial cell differentiation and axonal network formation during neurogenesis. It promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also, this protein induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Recombinant mouse METRN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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