MHC Class-I chain related gene A (MICA), human

Category: Proteins
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12-4415
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Product Name MHC Class-I chain related gene A (MICA), human
Description Recombinant human MICA (rHuMICA). rHuMICA is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. rHuMICA produced in E.Coli is a single, non-glycosylated polypeptide chain containing 320 amino acids and having a molecular mass of 36kDa. The sequence contains the extracellular domain of the mature human MICA (amino acid residues Ala23 Gln308).
Synonyms Neutrophil gelatinase-associated lipocalin, NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3, LCN2
Molecular Weight 36 kDa
Biological Activity Measured by its ability to bind MICA antibody in a ELISA.
Form Purified, no additives
Purity > 95% by SDS-PAGE
Storage 2-8C for immediate use, or at -2°C (aliquot)
Supplier ARP

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