| Product Name | MIEF1 Antibody, Biotin conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against MIEF1 conjugated to Biotin |
| Synonyms | MIEF1 antibody; MID51 antibody; SMCR7L antibody; Mitochondrial dynamics protein MID51 antibody; Mitochondrial dynamics protein of 51 kDa antibody; Mitochondrial elongation factor 1 antibody; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like antibody; SMCR7-like protein antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human Mitochondrial dynamics protein MID51 protein (51-309AA) |
| Isotype | IgG |
| Target | MIEF1 |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9NQG6 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L. |
| Supplier | Cusabio |
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