| Product Name | MOG (35-55) (rat) |
|---|---|
| Description | MOG (35-55) (rat) is a fragment of myelin oligodendrocyte glycoprotein (MOG), a transmembrane glycoprotein expressed at the surface of oligodendrocyte cells and on the outermost surface of the myelin sheath. MOG (35-55) (rat) is highly encephalitogenic, inducing strong T-cell and B-cell responses. As MOG (35-55) (rat) injection produces relapsing-remitting neurologic disease with clinical, histopathologic and immune similarities to multiple sclerosis, MOG induced demyelination is used as a model for MS research. |
| Synonyms | 149635-73-4, H-MEVGWYRSPFSRVVHLYRNGK-OH, MEVGWYRSPFSRVVHLYRNGK, MOG, MOG (35-55) (rat), MS, NR-020, NR020, demyelination, encephalitogenic, multiple sclerosis, myelin oligodendrocyte glycoprotein |
| Molecular Weight | 2582 Da |
| Target | Epitopes |
| Amino Acid Sequence | MEVGWYRSPFSRVVHLYRNGK |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Cas Number | 149635-73-4 |
| Storage | Store dark, frozen and desiccated |
| Notes | Modifications: None |
| References |
Oliver et al (2003) Rat and Human Myelin Oligodendrocyte Glycoproteins Induce Experimental Autoimmune Encephalomyelitis by Different Mechanisms in C57BL/6 Mice. J. Immunol. 171 (1) 462 PMID: 12817031Casella et al (2016) IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo. J. Neuroinflamm. 13 139 PMID: 27266518 Related areasAll myelin peptides >All immunology categories > |
| Supplier | Isca Biochemicals Limited |
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