| Product Name | Mouse anti-Actin, Muscle Specific, clone HHF35 |
|---|---|
| Description | Mouse anti-Actin, Muscle Specific, clone HHF35 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | HHF35 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1-k |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes |
The antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Muscle Specific Actin is a part of the actin family of proteins which are highly conserved, major components of the cytoskeleton. Anti-Muscle Specific Actin immunohistochemical reactivity is seen in skeletal, cardiac, and smooth muscle cells and can be seen in neoplasms with muscle differentiation such as leiomyomas and rhabdomyosarcomas. In contrast, antiMuscle Specific Actin reactivity is typically not seen in endothelial cells, connective tissues, carcinomas, melanomas, lymphomas and most nonmyogenic sarcomas |
| References | Gown AM, et al. Am J Pathol. 1986; 125:191. Schmidt RA, et al. Am J Pathol. 1988; 131:19-28. Azumi N, et al.Mod Pathol. 1988; 1:469-74. Rangdaeng S, et al. Am J Clin Pathol. 1991; 96:32-45. Tsukada T, et al. Am J Pathol. 1987; 127:389-402 |
| Supplier | MONOSAN |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
