| Product Name | Mouse anti-Alpha Fetoprotein (AFP), clone D10 (Monoclonal) |
|---|---|
| Description | Mouse anti-Alpha Fetoprotein (AFP), clone D10 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | D10 |
| Immunogen | alpha fetoprotein isolated from serum of hepatoma patients |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-Fr, ELISA, FC, IF |
| Working Dilutions | ,,, |
| Diluent Buffer | PBS with 0.02% sodium azide |
| Concentration | 100 ug/ml |
| Storage | 2-8°C |
| Notes | D10 has been characterized in the ISOBM TD-2 workshop and assigned by K. Nustad to group D of a cluster of 6 major epitopes of human alpha fetoprotein. Human alpha fetoprotein is an oncofetal protein of 70 kDa. It is expressed in fetal liver and is normally absent in healthy adult tissues. It is positive on all yolk sac tumors, on some other germ cell tumors and on hepatocellular carcinomas. |
| References | Tsung K., et al. J. Immunol. Methods 39: 363-368 (1980). Michell B.et al. Eur. J. Cancer Clin. Oncol. 19: 1239-1246 (1983). Yazova A.K. et al. Immunol. Lett. 25: 325-330 (1990). Nustad K. Et al. Tumor Biol 19: 293 -300 (1998). Yakimenko E.F. et al. Tumor Biol 19: 301-309 (1998) |
| Supplier | MONOSAN |
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