| Product Name | Mouse anti-Beta III Tubulin, clone TU-20 (Monoclonal) |
|---|---|
| Description | Mouse anti-Beta III Tubulin, clone TU-20 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | TU-20 |
| Immunogen | Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide. |
| Isotype | IgG1 |
| Reactivity | Canine, Human, Mouse, Porcine, Rat |
| Applications | FC, ICC, IHC-P, WB |
| Working Dilutions | ,,, |
| Diluent Buffer | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Concentration | 1 mg/ml |
| Storage | 2-8°C |
| Notes | The betaIII isoform of tubulin is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues. |
| References | Jirásek T, Cipro S, Musilová A, Kubecová M, Mandys V: Expression of class III beta-tubulin in colorectal carcinomas: an immunohistochemical study using TU-20 & TuJ-1 antibody. Indian J Med Res. 2009 Jan;129(1):89-94 |
| Supplier | MONOSAN |
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