Mouse anti-CA125 (Ovarian Cancer Antigen), clone OV185 (monoclonal)
| Product Name | Mouse anti-CA125 (Ovarian Cancer Antigen), clone OV185 (monoclonal) |
|---|---|
| Description | Mouse anti-CA125 (Ovarian Cancer Antigen), clone OV185 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Ov185:1 |
| Immunogen | A partially purified mucin fraction from a pool of cancer tissue from patients with epithelial ovarian cancer. |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:100) |
| Diluent Buffer | Purified in PBS, 1% BSA and 15 mM sodium azide |
| Concentration | Greater than or equal to 12.5 mg/L |
| Storage | 2-8°C |
| Notes | CA125 antigen is usually associated with ovarian epithelial malignancies. Serum assays are widely used to detect this protein in the monitoring of ovarian cancers. CA125 antigen may also be detected by immunohistochemistry and expression has been found in neoplasms such as seminal vesicle carcinoma and anaplastic lymphoma. CA125 antigen is not found exclusively in malignant tumors. CA125 is also known as MUC16. |
| References | Weng D et al. Int. Journal of Cancer. 2011; 129:1990-2001. Gabriel M et al. Gynakol Geburtshilfliche Rundsch. 2000; 40(3-4):140-144. Gabriel M et al. Ginekol Pol. 1999; 70(11):819-823. Keen CE et al.Histopathology. 1999; 34:113-117 |
| Supplier | MONOSAN |
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