| Product Name | Mouse Anti-cardiolipin antibody IgA (ACA-IgA) ELISA Kit |
|---|---|
| Description | Mouse Anti-cardiolipin antibody IgA (ACA-IgA) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ACA-IgA. No significant cross-reactivity or interference between Mouse ACA-IgA and analogues was observed. Cardiolipin is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition. The name ‘cardiolipin’ is derived from the fact that it was first found in animal hearts. It was first isolated from beef heart in the early 1940s. In mammalian cells, cardiolipin (CL) is found almost exclusively in the inner mitochondrial membrane where it is essential for the optimal function of numerous enzymes that are involved in mitochondrial energy metabolism.Cardiolipin is a kind of diphosphatidylglycerol lipid. Two phosphatidylglycerols connect with a glycerol backbone in the center to form a dimmeric structure. So it has four alkyl groups and potentially carries two negative charges. As there are four distinct alkyl chains in cardiolipin, the potential for complexity of this molecule species is enormous. This Mouse Anti-cardiolipin antibody IgA (ACA-IgA) ELISA Kit employs the competitive enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with an antibody specific to ACA-IgA. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated ACA-IgA and incubated. The competitive inhibition reaction is launched between with HRP labeled ACA-IgA and unlabeled ACA-IgA with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of ACA-IgA in the sample. The color development is stopped and the intensity of the color is measured. |
| Synonyms | ACA-IgA |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Mouse |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Storage | 2-8°C |
| Background | Cardiolipin is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition. The name ‘cardiolipin’ is derived from the fact that it was first found in animal hearts. It was first isolated from beef heart in the early 1940s. In mammalian cells, cardiolipin (CL) is found almost exclusively in the inner mitochondrial membrane where it is essential for the optimal function of numerous enzymes that are involved in mitochondrial energy metabolism.Cardiolipin is a kind of diphosphatidylglycerol lipid. Two phosphatidylglycerols connect with a glycerol backbone in the center to form a dimmeric structure. So it has four alkyl groups and potentially carries two negative charges. As there are four distinct alkyl chains in cardiolipin, the potential for complexity of this molecule species is enormous. |
| Supplier | Abbkine |
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