| Product Name | Mouse anti-CD10, clone 56C6 (Monoclonal) |
|---|---|
| Description | Mouse anti-CD10, clone 56C6 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 56C6 |
| Immunogen | Recombinant protein encoding external domain of human CD10 |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:10-1:50) |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Common acute lymphoblastic leukemia antigen (CALLA / CD10) is a useful marker for the characterization of childhood leukemia and B cell lymphomas. This antibody reacts with antigen of lymphoblastic, Burkitt's, and follicular lymphomas; and chronic myelocytic leukemia. Also, Anti-CD10 detects the antigen of glomerular epithelial cells and the brush border of the proximal tubules; this characteristic may be helpful in interpreting renal ontogenesis in conjunction with other markers. Other non-lymphoid cells that are reactive with CD10 are breast myoepithelial cells, bile canaliculi, neutrophils and small population of bone marrow cells, fetal small intestine epithelium, and normal fibroblasts. |
| References | Maguer-Satta V, et al.. Stem Cells. 2011; 29:389-96. Laurent C, et al. 2010; 95: 356-8. Onak NK, et al.. Turk J Med Sci. 2010; 40:177-84. Chu P, et al. Am J Clin Pathol. 2000; 113: 374-82 |
| Supplier | MONOSAN |
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