| Product Name | Mouse anti-CD11c, clone 5D11 (monoclonal) |
|---|---|
| Description | Mouse anti-CD11c, clone 5D11 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5D11 |
| Immunogen | Prokaryotic recombinant protein containing 258 amino acids from the N-terminus of the external domain of the CD11c molecule. |
| Isotype | IgG2a |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:100) |
| Diluent Buffer | Tissue culture supernatant with sodium azide |
| Concentration | Greater than or equal to 30 mg/L |
| Storage | 2-8°C |
| Notes | CD11c is a member of the leukocyte integrin family of adhesion proteins. It is reported to be expressed in normal tissues, mainly on myeloid cells, for example, in bone marrow myelocytes, premyelocytes, metamyelocytes, non-segmented and segmented neutrophils with high levels reported on tissue macrophages and monocytes and with lowest levels in granulocytes. It is also reported to be expressed on NK cells, activated T cells, lymphoid cell lines, including hairy cell leukemias and a proportion of interdigitating dendritic cells. |
| References | Barth TFE et al. Journal of Pathology. 2007; 211:305-313. Venkatraman L et al. Modern Pathology. 2005; 18: 255A-256A 1183 Supplement 1 |
| Supplier | MONOSAN |
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