| Product Name | Mouse anti-CD19, clone BT51E (monoclonal) |
|---|---|
| Description | Mouse anti-CD19, clone BT51E (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | BT51E |
| Immunogen | A prokaryotic fusion protein containing part of the C-terminal region of the human CD19 molecule. |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:50) |
| Diluent Buffer | Tissue culture supernatant with sodium azide |
| Concentration | Greater than or equal to 35 mg/L |
| Storage | 2-8°C |
| Notes | CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. It is a single chain glycoprotein present on the surface of B lymphocytes and follicular dendritic cells of the hematopoietic system. CD19 is a crucial regulator in B cell development, activation and differentiation. On B cells, CD19 associates with CD21, CD81 and CD225 (Leu-13) forming a signal transduction complex. CD19 is expressed from the earliest recognizable B cell lineage stage, through development to B cell differentiation but is lost on maturation to plasma cells. |
| References | Fujimoto M and Sato S. Journal of Dermatological Science. 2007; 46:1-9. Otero D et al. The Journal of Immunology. 2003; 170: 73-83. Fujimoto M et al. Seminars in Immunology. 1998; 10:267-277 |
| Supplier | MONOSAN |
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