| Product Name | Mouse anti-CD20, clone L26 (monoclonal) |
|---|---|
| Description | Mouse anti-CD20, clone L26 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | L26 |
| Immunogen | Human tonsil B cells. |
| Isotype | IgG2a, kappa |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:100-1:200) |
| Diluent Buffer | Tissue culture supernatant with sodium azide |
| Concentration | Greater than or equal to 95 mg/L |
| Storage | 2-8°C |
| Notes | The CD20 antigen is a non-glycosylated phosphoprotein of approximately 33kD which is expressed on normal and malignant human B cells and is thought to act as a receptor during B cell activation and differentiation. CD20 antigen has been reported to be expressed on normal B cells from peripheral blood, lymph node, spleen, tonsil, bone marrow, acute leukemias and chronic lymphocytic leukemias.An intracytoplasmic epitope localised on the human CD20 molecule. Reacts predominantly with a 33 kD polypeptide, but also with a minor component of 30 kD. |
| References | Mason DY et al. American Journal of Pathology. 1990; 136(6):1215–1222. Cartun RW et al. American Journal of Pathology. 1987; 129(3):415–421. Norton AJ and Isaacson PG. Journal of Clinical Pathology. 1987; 40:1405–1412. Ishii Y et al. Clinical Experimental Immunology. 1984; 58:183–192 |
| Supplier | MONOSAN |
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