| Product Name | Mouse anti-CD22, clone RFB4, R-PE (Monoclonal) |
|---|---|
| Description | Mouse anti-CD22, clone RFB4, R-PE (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | RFB4 |
| Conjugate | RPE |
| Immunogen | Human CD22 |
| Isotype | IgG1 |
| Reactivity | Canine, Human |
| Applications | FC |
| Diluent Buffer | PBS with 4mg/ml BSA and 0.1% sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa. CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes. CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen. Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias. |
| References | Bechanova V et al. Am Assoc for Cancer Res 2015. Pantelyushin S et al. J of Int Soc for Anal Cytol. 2020 |
| Supplier | MONOSAN |
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