| Product Name | Mouse anti-CD227, clone C595/NCRC48, FITC (Monoclonal) |
|---|---|
| Description | Mouse anti-CD227, clone C595/NCRC48, FITC (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | C595 (NCRC48) |
| Conjugate | FITC |
| Immunogen | Urinary MUC-1 mucin. |
| Isotype | IgG3 |
| Reactivity | Human |
| Applications | FC, IF |
| Working Dilutions | , |
| Diluent Buffer | PBS with 0.09% sodium azide and 1% BSA |
| Concentration | 0.1 mg/ml |
| Storage | 2-8°C |
| Notes | Mouse anti Human CD227 antibody, clone C595 (NCRC48) recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases.Mouse anti Human CD227 antibody, clone C595 recognizes the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin. |
| References | Denton, G. et al. (1997). Br. J. Cancer. 76 (5): 614-21 |
| Supplier | MONOSAN |
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