| Product Name | Mouse anti-CD25, clone 4C9 |
|---|---|
| Description | Mouse anti-CD25, clone 4C9 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 4C9 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | CD25, Interleukin-2 receptor alpha chain, is the alpha subunit of the cell surface receptor which regulates regulatory T-cells. CD25 has been detected in various hematological malignancies including adult T-cell leukemia/lymphoma, and hairy cell leukemia. MON 3230 has also been useful in identifying mast cells in skin biopsies in the setting of Urticaria Pigmentosa, which is predictive of Systemic Mastocytosis. |
| References | Hahn HP, et al. Am J Surg Pathol. 2007 Nov;31(11):1669-76. Hollmann TJ, et al. Am J Surg Pathol. 2008 Jan;32(1):139-45. Létourneau S, et al. Clin Immunol. 2009; 123:758-62. De Totero D, et al.. Leuk Lymphoma. 1994; 104:412-9. Qayyum S, et al. Archives of Pathology & Lab Med. 2014; 138:282-6 |
| Supplier | MONOSAN |
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