| Product Name | Mouse anti-CD26, clone 202.36 (Monoclonal) |
|---|---|
| Description | Mouse anti-CD26, clone 202.36 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 202-36 |
| Immunogen | T-cell clone |
| Isotype | IgG2b |
| Reactivity | Human, Rat |
| Applications | IHC-Fr, FC, IF, WB |
| Working Dilutions | ,,, |
| Diluent Buffer | PBS with 0.02% sodium azide |
| Concentration | 100 ug/ml |
| Storage | 2-8°C |
| Notes | 202-36 Reacts with human CD26 (Dipeptidyl peptidase IV), a 110 kDa protein which occurs in the cell membrane of T-lymphocyte and is upregulated after activation. CD26 is also present on endothelial cells and also expressed on activated B-cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Crosslinking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with deglycosylated froms. It does not prevent ADA binding to CD26. The mAb was clustered at the VIth WLDA. |
| References | Kishimoto T. et al., eds. Leukocyte Typing VI, Garland Publishing, (1997) |
| Supplier | MONOSAN |
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