| Product Name | Mouse anti-CD3, clone SPV-T3b (Monoclonal) |
|---|---|
| Description | Mouse anti-CD3, clone SPV-T3b (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPV-T3b |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG2a |
| Reactivity | Human |
| Applications | IHC-Fr, IF |
| Working Dilutions | , |
| Diluent Buffer | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration | 100 ug/ ml |
| Storage | 2-8°C |
| Notes | CD3 is presented on all resting and activated human T-cells, on T-leukemia cells and a proportion of human thymocytes. CD3 plays an important role in the assembly and expression of the T-cell receptor complex. Furthermore it functions as a signal transductor. SPV-T3b reacts with human CD3 also designated as T3 with a molecular weight of 20-26 kDa. SPV-T3b recognizes also the T3 molecular complex. |
| References | Spits; H et al. Hybridoma 1983; 2: 423. Geisler, C et al Scand J Immunol 1988, 28: 741. Parsey; M et al. J Immunol 1993; 151: 1881. Molina I et al. J Immunol 1993; 151: 4383. Lien E et al. J Biol Chem 1999; 274: 33419 |
| Supplier | MONOSAN |
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