| Product Name | Mouse anti-CD30, clone Ber-H2 |
|---|---|
| Description | Mouse anti-CD30, clone Ber-H2 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Ber-H2 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1-k |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes |
The antibody detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classic Hodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positive T-cell lymphoproliferative disorders and in embryonal carcinomas. Occasionally diffuse large B-cell lymphoma stains with this antibody. This antibody also stains plasma cells in paraffin-embedded tissue as well as reactive immunoblasts. The staining pattern of anti-CD30 in lymphoma and embryonal carcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation in location, and the latter being membranous only. |
| References | Schwarting R, et al., Blood 1989 (74):1678-1689. Fonatsch C, et al., Genomics 1992 (14):825-826. George DH et al. Am J Surg Pathol. 2003 Apr;27(4): 487-93. Hedvat CV et al. Hum Pathol. 2002 Oct;33(10): 968-74. Dabbs DJ. 4th Edition Saunders Elsevier. 2014; p702 |
| Supplier | MONOSAN |
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