| Product Name | Mouse anti-CD30, clone JCM182 (monoclonal) |
|---|---|
| Description | Mouse anti-CD30, clone JCM182 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | JCM182 |
| Immunogen | Prokaryotic recombinant protein corresponding to the internal domain of the protein of the human CD30 molecule. |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:100) |
| Diluent Buffer | Tissue culture supernatant with sodium azide |
| Concentration | Greater than or equal to 72 mg/L |
| Storage | 2-8°C |
| Notes | The CD30 antigen is a single chain glycoprotein with a molecular weight of 120 kD. CD30 antigen is known to act as a receptor for a cytokine ligand, CD30L, and may also play a role in the regulation of cellular growth and transformation. CD30 antigen is reported to be expressed on the surface of multinucleated Reed Sternberg cells, mononuclear Hodgkin's cells and in the majority of anaplastic large cell lymphomas. The CD30 antigen is expressed in non-Hodgkin's lymphoma and virally transformed cells, for example, EBV-transformed B cells. |
| References | Kennedy M et al. Immunology. 2006; 118: 143-152. Chiarle R et al. Clinical Immunology. 1999; 90(2):157-164 |
| Supplier | MONOSAN |
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