Mouse anti-CD37, clone IPO-24 (Monoclonal)

Category: Antibodies
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MON1035
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Product Name Mouse anti-CD37, clone IPO-24 (Monoclonal)
Description Mouse anti-CD37, clone IPO-24 (Monoclonal)
Host Mouse
Clonality Monoclonal
Clone IPO-24
Immunogen spleen cells of a patient with hairy cell leukemia
Isotype IgG2b
Reactivity Human
Applications IHC-Fr, FC, IF
Working Dilutions ,,
Diluent Buffer PBS with 0.02% sodium azide
Concentration 100 ug/ml
Storage 2-8°C
Notes IPO-24 reacts with CD37, a B lineage restricted antigen, strongly expressed throughout B-cell ontogeny from pre B-cell until plasmablasts. Plasma cells are negative. IPO-24 reacts with human B-cell lines Daudi, Raji, Namalva, Ramos and CABIL, whereas T-cell lines CEM, Molt-4, Jurkat, MT-4, H9 and non-lymphoid cell lines MeWo and A-431 are negative. IPO-24 stains Bcell follicles and the most strongly labelled elements are mantle zone lymphoid cells. Neutrophils, macrophages, thymocytes and dendritic reticulum cells are negative.
References G. Moldenhauer G. et al., CD37 Workshop Panel report in: Schlossman et al., Leucocyte Typing V, B9, 544-545, (1995). Sidorenko S.P. et al., J. Tumor Marker Oncology 5: 232 (1990). Sidorenko S.P. et al., Haemat. Transfusiol. 35 N4: 19-22 (1990). Sidorenko S.P. et al., Neoplasma 39(1):3-9 (1992)
Supplier MONOSAN

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