| Product Name | Mouse anti-CD38, clone HIT2, FITC (Monoclonal) |
|---|---|
| Description | Mouse anti-CD38, clone HIT2, FITC (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | HIT2 |
| Conjugate | FITC |
| Immunogen | Human CD38 |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | FC |
| Diluent Buffer | PBS with 4mg/ml BSA and 0.1% sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. |
| References | de Oliveira AL et al. Immunol 2013. Zhang et al. Exp Hematol 2000. Grammer AC et al. J Immunol 1999. Denning-Kendall PA et al. Brit J of Haematol 1999. Hryhorenko EA et al. Photochem and photobiol 1998 |
| Supplier | MONOSAN |
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