| Product Name | Mouse anti-CD45, clone 2B11 & PD7/26 |
|---|---|
| Description | Mouse anti-CD45, clone 2B11 & PD7/26 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2B11 & PD7/26 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1-k |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Anti-CD45 (anti-leukocyte common antigen) is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody; therefore a positive result is highly indicative of hematolymphoid origin. Certain types of hematolymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors. |
| References | Mason, DY, Am Pathol 1987;128:1-4. Hall PA, Histopathology 1988;13:149-160. Kurtin, PJ, Hum Path 1985;16:353-365. Maluf HM et al. Mod Pathol. 1995 Feb; 8(2): 155-9. Caballero T et al. J Clin Pathol. 1995 Aug;48(8): 743-8 |
| Supplier | MONOSAN |
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