| Product Name | Mouse anti-CD56, clone MEM-188, Tri-Color (Monoclonal) |
|---|---|
| Description | Mouse anti-CD56, clone MEM-188, Tri-Color (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | MEM-188 |
| Conjugate | Tri-Color |
| Immunogen | Human CD56 |
| Isotype | IgG2a, k |
| Reactivity | Human |
| Applications | FC |
| Diluent Buffer | PBS with 4mg/ml BSA, 10% sucrose and 0.1% sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. |
| References | Lanier, L.L., Test, R., Bindl, J. and Philipps, J.H. 1989 J. Exp. Med. 169:2233 |
| Supplier | MONOSAN |
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