| Product Name | Mouse anti-CD57, clone NK-1 (Monoclonal) |
|---|---|
| Description | Mouse anti-CD57, clone NK-1 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | NK-1 |
| Immunogen | preparation of HSB-2 T cell line |
| Isotype | IgM |
| Reactivity | Human |
| Applications | IHC-Fr, FC, IF, IHC-P, WB |
| Working Dilutions | ,,,, |
| Diluent Buffer | PBS with 0.02% sodium azide |
| Concentration | 100 ug/ul |
| Storage | 2-8°C |
| Notes | NK-1 reacts with CD57, a 110 kDa antigen present on the surface of human NK-cells and Tcell subsets. In adult peripheral blood 20% of mononuclear cells are positive. Other positive tissues include peripheral nerves (myelin-associated glycoprotein) and prostate. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastomas. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA. |
| References | Abo T et al J. Immunol 127:1024 (1981). Abo T et al. J Immunol 129(4):1752-7 (1982). Abo T et al. J Immunol 129(4):1758-61 (1982). McGarry, RC et al. Nature 306:376 (1983). Lanier, LL et al. J. Immunology 131:1789 (1983) |
| Supplier | MONOSAN |
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