| Product Name | Mouse anti-CD79b, clone JS01 (monoclonal) |
|---|---|
| Description | Mouse anti-CD79b, clone JS01 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | JS01 |
| Immunogen | A recombinant protein containing 48 amino acids of the cytoplasmic domain of the CD79b molecule |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:40) |
| Diluent Buffer | Tissue culture supernatant with 15mM sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | CD79b, also known as B29 and Ig-beta is thought to function in the cellular activation and signaling that occurs when surface immunoglobulin (Ig) on B cells binds antigen or becomes cross-linked by anti-Ig antibody. This function occurs with the formation of a membrane signaling complex that is associated with Ig at the surface of B cells. CD79b, together with CD79a, forms the B cell antigen receptor (mlg) complex. |
| References | Matutes E. Journal of Clinical Pathology. 55: 180–183 (2002). McCarron K F et al. American Journal of Clinical Pathology. 113 (6): 805–813 (2000). Moreau E J et al. American Journal of Clinical Pathology. 108: 378–382 (1997) |
| Supplier | MONOSAN |
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