| Product Name | Mouse anti-CD8, clone 4B11 (monoclonal) |
|---|---|
| Description | Mouse anti-CD8, clone 4B11 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 4B11 |
| Immunogen | Peptide corresponding to the alpha chain cytoplasmic portion of the human CD8 molecule. |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:50) |
| Diluent Buffer | Tissue culture supernatant with sodium azide |
| Concentration | Greater than or equal to 28 mg/L |
| Storage | 2-8°C |
| Notes | The CD8 molecule is composed of two chains and has a molecular weight of 32 kD. It is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35% of human peripheral blood lymphocytes.The CD8 antigen is reported to be detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15-30% of bone marrow cells. |
| References | Kemp RA et al. Journal of Experimental & Clinical Cancer Research. 2011;30(1):78. Michel S et al. British Journal of Cancer. 2008;99(11):1867-1873. Williamson SLH et al. American Journal of Pathology 1998,152(6):1421-1426 |
| Supplier | MONOSAN |
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