| Product Name | Mouse anti-Cdk4, clone DCS-31 (Monoclonal) |
|---|---|
| Description | Mouse anti-Cdk4, clone DCS-31 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | DCS-31 |
| Immunogen | Purified recombinant cdk4 protein |
| Isotype | IgG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | FC, ICC, IP, WB |
| Working Dilutions | ,,, |
| Diluent Buffer | PBS with 0.2% BSA and 0.09% sodium azide |
| Concentration | 0.2 mg/ml |
| Storage | 2-8°C |
| Notes | Antibody reacts with epitope at aa 16-35. DK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). |
| References | Li XR et al. Exp and Ther Medicine 2017. Kennedy AL et al. Oncotarget 2015. Clay MR et al. Am J of Surg Pathol 2016. Weingertner N et al. AIMM 2015. Sugita S et al. Diagn Pathol 2016 |
| Supplier | MONOSAN |
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