Mouse anti-Cytokeratin 5&6 + TTF-1, clones D5/16B4 & 8G7G3/1
| Product Name | Mouse anti-Cytokeratin 5&6 + TTF-1, clones D5/16B4 & 8G7G3/1 |
|---|---|
| Description | Mouse anti-Cytokeratin 5&6 + TTF-1, clones D5/16B4 & 8G7G3/1 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | D5/16B4 & 8G7G3/1 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1/IgG1/IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Anti-Cytokeratin 5 & 6 is a marker for eptihelioid mesotheliomas. Anti-Cytokeratin 5 & 6 stains the cytoplasm of such cells. Anti-TTF-1 stains the nuclei in the case of lung adenocarcinomas and is negative in nearly all mesotheliomas. The nuclear vs. cytoplasmic staining pattern of this cocktail can be useful in distinguishing between mesothelioma and adenocarcinoma of the lung. |
| References | Ordóñez NG. Am J Surg Pathol. 1998; 22:1215-21. Jang KY, et al. Anal Quant Cytol Histol; 2001; 23:400-4. Srodon M, et al. Hum Pathol. 2002; 33:642-5. Abutaily AS, et al. J Clin Pathol. 2002; 55:662-8. Bejarano PA, et al. Arch Pathol Lab Med. 2003; 127:193-5 |
| Supplier | MONOSAN |
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