| Product Name | Mouse anti-Cytokeratin 14, clone LL002 (Monoclonal) |
|---|---|
| Description | Mouse anti-Cytokeratin 14, clone LL002 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | LL002 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG3 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:100-1:500) |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Cytokeratin 14 is a member of the Type I family of cytokeratins and is generally expressed in the basal cell layer of squamous epithelium. The cytokeratin 14 protein forms a heterotetramer with homodimers of cytokeratin 5 to contribute to the structural integrity of the intracellular cytoskeletal network. Anticytokeratin 14 has immunohistochemical utility as an aid in distinguishing squamous cell carcinomas from other tumors of epithelial origin. |
| References | Reis-Filho JS et al. Appl Immunohistochem Mol Morphol; 11(1):1-8 (2003). Chu PG et al. Histopathology ; 39(1):9-16 (2001). Chu PG, Weiss LM. Histopathology; 39(5):455-62 (2001). Dabbs David J. Diagnostic Immunohistochemistry. Churchill-Livingstone. p. 166-176 (2002) |
| Supplier | MONOSAN |
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