Mouse anti-Delta chain of human Immunoglobulin D, clone DRN1C (monoclonal)
| Product Name | Mouse anti-Delta chain of human Immunoglobulin D, clone DRN1C (monoclonal) |
|---|---|
| Description | Mouse anti-Delta chain of human Immunoglobulin D, clone DRN1C (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | DRN1C |
| Immunogen | Prokaryotic recombinant protein corresponding to 222 amino acids of the N terminus of the delta heavy chain constant region of the human immunoglobulin D molecule. |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:1000) |
| Diluent Buffer | Tissue culture supernatant with Sodium azide |
| Concentration | Greater than or equal to 133 mg/L |
| Storage | 2-8°C |
| Notes | IgD, together with IgM, are the major immunoglobulins expressed on the surface of B cells where it seems they may operate as mutually interacting antigen receptors for the control of lymphocyte activation and suppression. The greater susceptibility of IgD to proteolysis in combination with antigen could well be implicated in such a function. The use of PBS-based diluents may result in increased background staining. Clone DRN1C was developed to produce reduced background staining that is associated with polyclonal antibodies on paraffin sections. |
| References | Geisberger R et al. Immunology. 2006; 118:429-437. Preud’homme J et al. Molecular Immunology. 2000; 37:871-887. Vladutiu A. Clinical and diagnostic laboratory immunology. 2000; 7(2):131-140 |
| Supplier | MONOSAN |
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