Mouse anti-Desmin (Liquid Primary Antibody), clone DE-R-11 (monoclonal)
| Product Name | Mouse anti-Desmin (Liquid Primary Antibody), clone DE-R-11 (monoclonal) |
|---|---|
| Description | Mouse anti-Desmin (Liquid Primary Antibody), clone DE-R-11 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | DE-R-11 |
| Immunogen | Purified porcine desmin. |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:200) |
| Diluent Buffer | Tissue culture supernatant with Sodium azide |
| Concentration | Greater than or equal to 27 mg/L |
| Storage | 2-8°C |
| Notes | DES-DERII reacts with an 18 kD rod piece of the intermediate filament protein desmin (53 kD) in muscle cells. The antibody does not appear to recognize other intermediate filament proteins. In normal tissues, Clone DE-R-11 reacts with both striated (skeletal and cardiac) and smooth muscle cells. The labeling is confined to the Z bands in skeletal and cardiac muscle giving a characteristic striated appearance. |
| References | Beaton LJ et al. Journal of Physiology. 2002; 544(Pt3):849-859. Barber A et al.The FASEB Journal. 2001; 15:1158-1168. Debus E et al.The EMBO Journal. 1983; 2(12):2305-2312. Baghdiguian S et al. Nature Medicine. 1999; 5(5):503-511. Lyall F et al. American Journal of Pathology. 2001; 159(5):1827-1838 |
| Supplier | MONOSAN |
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