Mouse anti-Dystrophin (Rod Domain), clone DY4/6D3 (monoclonal)
| Product Name | Mouse anti-Dystrophin (Rod Domain), clone DY4/6D3 (monoclonal) |
|---|---|
| Description | Mouse anti-Dystrophin (Rod Domain), clone DY4/6D3 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Dy4/6D3 |
| Immunogen | Bacterial fusion protein |
| Isotype | IgG2a |
| Reactivity | Canine, Hamster, Human, Mouse, Porcine, Rabbit, Rat |
| Applications | IHC-Fr |
| Diluent Buffer | Lyophilized |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Dystrophin is the 427kD protein product of the DMD gene located on the X chromosome at position Xp21. Analyte Specific Reagent. Analytical and performance characteristics are not established. Product is a lyophilized tissue culture supernatant containing sodium azide as a preservative. The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label. Reacts strongly with the rod domain (between amino acids 1181 and 1388) of human dystrophin. Also reacts with skeletal, cardiac and smooth muscle dystrophin from normal mouse, rat, rabbit, dog, hamster and pig. No reactivity with mdx mouse tissue of DMD/BMD patients who have a gene deletion which removes the antibody binding site. No reaction is seen with chicken dystrophin. |
| References | Marafioti T et al. American Journal of Pathology. 162 (3): 861–871 (2003. Hess J et al. Molecular and Cellular Biology. 21 (5): 1531–1539 (2001). Re D et al. Cancer Research. 61 (5): 2080–2084 (2001). Luo Y and Roeder R G. Molecular and Cellular Biology. 15 (8): 4115–4124 (1995) |
| Supplier | MONOSAN |
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