| Product Name | Mouse anti-EMA, clone E29 (Monoclonal) |
|---|---|
| Description | Mouse anti-EMA, clone E29 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | E29 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG2a-k, IgG1-k |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:100-1:500) |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes |
The antibody s a useful marker for staining many carcinomas. It stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and colorectal carcinoma. Hepatocellular carcinoma, adrenal carcinoma and embryonal carcinomas are consistently EMA negative, so keratin positivity with negative EMA favors one of these tumors. EMA is frequently positive in meningioma, which can be useful when distinguishing it from other intracranial neoplasms such as schwannomas. |
| References | Dearnaly DP, et al. Lancet 1983; 1271-4. Attanoos RL, et al. Histopathology. 2003; 43:231-8. Beer TW, et al. Histopathology. 2000; 37:218-23. Lee JS, et al. Acta Cytol. 1996; 40:631-6. Fraga M, et al. Am J Clin Pathol. 1995; 103:82-9 |
| Supplier | MONOSAN |
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