Mouse anti-Epithelial Membrane Antigen, clone GP1.4 (monoclonal)

Category: Antibodies
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MONX10475
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Product Name Mouse anti-Epithelial Membrane Antigen, clone GP1.4 (monoclonal)
Description Mouse anti-Epithelial Membrane Antigen, clone GP1.4 (monoclonal)
Host Mouse
Clonality Monoclonal
Clone GP1.4
Immunogen Human milk fat globule membrane.
Isotype IgG1
Reactivity Human
Applications IHC-P
Working Dilutions IHC-P (1:200)
Diluent Buffer Tissue culture supernatant with Sodium azide
Concentration Greater than or equal to 11 mg/L
Storage 2-8°C
Notes Epithelial membrane antigen (EMA), also known as episialin, is reported to be expressed in a variety of normal and neoplastic epithelia. It has been reported that markers to CD45 (LCA) when used in conjunction with markers to EMA are useful in labeling cells of lymphoid origin, whereas the combination of anti-cytokeratin antibodies together with EMA is useful to characterize cells of epithelial origin. EMA is also notably described to be expressed in a subset of Hodgkin's lymphomas.
References Kim JH et al. The Korean Journal of Pathology. 2002; 36:66–69. Kim GY et al. The Korean Journal of Pathology. 2002; 36:51–54. Kojima M et al. Modern Pathology. 2002; 15(7):750–758. Yokozaki H et al. Japanese Journal of Clinical Oncology. 2000; 30:101–104. Yoneda S et al. Histopathology. 1999; 35(1):19–30
Supplier MONOSAN

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