| Product Name | Mouse anti-Estrogen Receptor, clone 6F11 (monoclonal) |
|---|---|
| Description | Mouse anti-Estrogen Receptor, clone 6F11 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 6F11 |
| Immunogen | Prokaryotic recombinant protein corresponding to the full length alpha form of the human estrogen receptor molecule. |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:50) |
| Diluent Buffer | Tissue culture supernatant with Sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Estrogen receptor (ER) content of breast cancer tissue is an important parameter in the prediction of prognosis and response to endocrine therapy. The introduction of highly specific monoclonal antibodies to ER has allowed the determination of receptor status of breast tumors to be carried out in routine histopathology laboratories. |
| References | Bevitt DJ et al. Journal of Pathology 1997; 183(2), 228–232. Kaplan, PA et al. Am J Clin Pathol 2005: 276–280. Zafrani B et al. Histopathology 2000; 37(6), 536–545. Harvey JM et al. Journal of Clinical Oncology 1999; 17(5), 1474–1481. Khan SA et al.European Journal of Cancer 2000; 36(Suppl 4), S27–S28 |
| Supplier | MONOSAN |
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