Mouse anti-GCDFP-15, clone 23A3 (Monoclonal)

Category: Antibodies
Catalog
MON3283
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Product Name Mouse anti-GCDFP-15, clone 23A3 (Monoclonal)
Description Mouse anti-GCDFP-15, clone 23A3 (Monoclonal)
Host Mouse
Clonality Monoclonal
Clone 23A3
Immunogen Unknown or proprietery to MONOSAN and/or its suppliers
Isotype IgG2a
Reactivity Human
Applications IHC-P
Working Dilutions IHC-P (1:50-1:200)
Diluent Buffer Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Concentration n/a
Storage 2-8°C
Notes GCDFP-15 is a 15 kD glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, ear canal, and in salivary glands. GCDFP-15 positivity is seen in breast carcinomas. On the other hand, colorectal carcinomas, lung carcinoma, mesotheliomas rarely stain with this antibody. Because of its specificity for breast carcinoma, this antibody is often helpful in distinguishing metastasis of unknown primary.
References Mazoujian G, et al. Am J Pathol. 1983; 110:105-12. Liegl B, et al. Histopathology. 2007; 50:439-47. Bhargava R, et al. Am J Clin Pathol. 2007; 127:103-13. Tornos C, et al. Am J Surg Pathol. 2005; 29:1482-9. Takeda Y, et al. Arch Pathol Lab Med. 2008; 132:239-43
Supplier MONOSAN

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