Mouse anti-GnRH Receptor, clone F1G4 (Monoclonal)

Category: Antibodies
Catalog
MON8056
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Product Name Mouse anti-GnRH Receptor, clone F1G4 (Monoclonal)
Description Mouse anti-GnRH Receptor, clone F1G4 (Monoclonal)
Host Mouse
Clonality Monoclonal
Clone F1G4
Immunogen BSA-conjugated peptide corresponding to amino acids 1-29 of human GnRH receptor extracellular domain
Isotype IgG1
Reactivity Human, Rat
Applications IHC-Fr, ELISA, IHC-P, WB
Working Dilutions ,,,
Diluent Buffer PBS with 0.02% sodium azide
Concentration 100 ug/ml
Storage 2-8°C
Notes F1G4 reacts with GnRH receptors in the anterior pituitary. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinising hormone (LH) as well as follicle-stimulating hormone (FSH). The receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular, and intracellular loops characteristic of G protein couple receptors. Some cancers like ovarian and breast cancers sometimes carry GnRH receptors.
References Karande, A.A., et al., Molec. Cell. Endocrinol. 114: 51-56 (1995)
Supplier MONOSAN

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