| Product Name | Mouse anti-HLA-D, clone 7.5.10.1 (Monoclonal) |
|---|---|
| Description | Mouse anti-HLA-D, clone 7.5.10.1 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 7.5.10.1 |
| Immunogen | Human EVB-transformed B-cell line DR3/3 |
| Isotype | IgG2a |
| Reactivity | Human |
| Applications | IF |
| Working Dilutions | IF (1:5) |
| Diluent Buffer | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | The antibody reacts with a monomorphic determinant on MHC class II, HLA-D region molecules. It detects the molecules of the HLA-DR, DP and DQ loci. It inhibits the mixed lymphocyte culture. It also reacts with MHC class II molecules of various animals and is a useful tool for studies with dogs. The antibody is useful for the identification of HLA-D positive molecules using either microcytotoxicity testing or immunofluorescence/immunoperoxidase procedures. Furthermore, it was found useful for studies on functional aspects of MHC class II molecules. |
| References | Koning, F., et al., 1984, Human Immunology 9, 221. Koning, F., et al., 1985, Tissue Antigens 26, 100. Doveren, R.F., et al., 1986, Tissue Antigen 27, 87-98. Hauber, I., et al., 1995, J. Exp. Med 181, 1411-1423. Groenenwegen, G., et al., 1986, J. Exp. Med 164, 131-143 |
| Supplier | MONOSAN |
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