| Product Name | Mouse anti-HLA-DRw52, clone 7.3.19.1 (Monoclonal) |
|---|---|
| Description | Mouse anti-HLA-DRw52, clone 7.3.19.1 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 7.3.19.1 |
| Immunogen | Human HLA-DRw52 |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | IF |
| Working Dilutions | IF (1:10) |
| Diluent Buffer | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | The antibody reacts with a polymorphic determinant on HLA-DR molecules which is associated with DR3, DR5, and DRw6 (DRw52-like). It does not react with DRw8. The antibody reacts with part of the HLA-D molecules (29+34 kD). The determinant is strongly expressed on DR3 positive cells and more weakly on DR5 and DRw6 positive cells. The antibody is useful for HLA-DR typing and biochemical characterization of the DR52w positive molecules and functio¬nal studies. Cross reacts with Chimpanzee, Macaca-apes and gorilla. |
| References | Koning, F., et al., 1984, Human Immunology, 9, 221. Koning, F., et al., 1985, Disease Markers 2, 75. Ottenhoff, T.H.M., et al., 1985, Human Immunology, 13, 117. Bontrop, R.E., et al., 1990, J. Exp. Med. 172, 53. Verreck, F.A.W., et al., 1993, Eur. J. Immunol. 23, 1346 |
| Supplier | MONOSAN |
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