| Product Name | Mouse anti-Inhibin A, Clone AMY82 (monoclonal) |
|---|---|
| Description | Mouse anti-Inhibin A, Clone AMY82 (monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | AMY82 |
| Immunogen | Prokaryotic recombinant protein corresponding to 134 amino acids of the human inhibin alpha molecule. |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P (1:100) |
| Diluent Buffer | Tissue culture supernatant with 15mM Sodium azide |
| Concentration | Greater than or equal to 214 mg/L |
| Storage | 2-8°C |
| Notes | Inhibins and activins are members of the transforming growth factor beta (TGFβ) family of cytokines. Inhibins are heterodimers consisting of a common α-subunit linked to either a βA subunit ( α-βA, forming inhibin A) or a βB subunit ( α-βB, forming inhibin B). Activins share the β-subunit with the inhibins and may be homo or heterodimers of β-subunits forming activin A (βA-βA), activin AB (βA-βB) or activin B (βB-βB). The expression of the α-subunit, and therefore of inhibins appears to be more restricted than that of the β-subunit, and therefore of activins. Inhibins and activins play a role in the regulation of pituitary follicle stimulating hormone (FSH) secretion. |
| References | Robertson D et al. Endocrine-Related Cancer. 2004; 11:35–49. Bernard J et al. Recent Progress in Hormone Research. 2001; 56:417–450 |
| Supplier | MONOSAN |
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