| Product Name | Mouse anti-Keratin 5+8, clone RCK102 (Monoclonal) |
|---|---|
| Description | Mouse anti-Keratin 5+8, clone RCK102 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | RCK102 |
| Immunogen | Lung cancer cell preparation |
| Isotype | IgG1 |
| Reactivity | Canine, Hamster, Human, Mouse, Porcine, Rabbit, Rat |
| Applications | IHC-Fr, IF, IHC-P, WB |
| Working Dilutions | ,IHC-P (1:5-1:10),, |
| Diluent Buffer | Hybridoma cell culture supernatant containing 0.09% sodium azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes |
Mab RCK 102, directed against the 58 kD and 52.2 kD keratin proteins (keratins K5 and K8; formerly also designated cytokeratins 5 and 8 in the Moll catalogue of keratins), reacts with all epithelial cell types. No reaction is observed in non-epithelial tissues. The antibody can be used for the discrimination of carcinomas from non-epithelial tumors such as lymphomas, sarcomas and neural tumors. RCK 102 is applicable on frozen and paraffin-embedded tissue. Formalin fixation may cause antigen denaturation or masking. Therefore, protease digestion is necessary prior to antibody application. Positive control: Skin, cervix. |
| References | Broers, J.L.V., et al., 1986, J. cell Science 83, 37-60. |
| Supplier | MONOSAN |
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